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It starts when an intracellu-lar membrane (often part of sER cistern) wraps aroundan organelle or portion of cytoplasm, forming a closeddouble membrane-bound vacuole. Thiscatheter can be opened to drainage or capped to simply serve as a stent of the appendicealstoma during healing.

In this context it can avoid the need toescalate the existing sedation a patient is on. The balance betweendonor anti-tumor T cells and GVHD-inducing T cells is of critical importance to the survivalof the transplant recipient (Thompson 2013)

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